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NAPSRx Final Exam Question and Answers

NAPSRx Final Exam Question and Answers

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NAPSRx Final Exam Question and Answers

NAPSRx Final Exam Question and Answers

1. How are drugs sorted into therapeutic groups and classes?
A. first by the conditions that they are used to treat. and then by their mechanisms of action
B. first by their mechanisms of action. and then by their therapeutic effects
C. first by their side effects. and then by their therapeutic effects
D. first by their toxicity. and then by their effectiveness


2. Bone marrow transplants…
A. require that the patient first undergo chemotherapy or radiation to kill the diseased stem cells and promote white blood cell production.
B. are a type of stem cell therapy. unless patient’s own cells are reinjected.
C. are always a type of stem cell therapy.
D. can help people with leukemia. a condition in which the body does not produce enough white blood cells.


3. What does AMA stand for?
A. American Medical Academy
B. American Medical Accreditation
C. American Medical Association
D. Association of Medical Assistants


4. What section of a drug’s package insert describes situations in which the drug should not be used because the risks outweigh the therapeutic benefits?
A. adverse reactions
B. contraindications
C. overdosage
D. warning/precautions


5 What is tertiary care?
A. adding medications together to achieve a better clinical effect
B. highly specialized medical and surgical care provided by a large medical center for unusual or complex medical problems NAPSRx Final Exam Question and Answers
C. receiving medical or surgical care that does not require an overnight stay in the treatment facility
D. seeing a physician for routine checkups and general healthcare


6. Which of the following is NOT one of the stages in the classic approach to brand development strategy covered in your manual?
A. brand personality
B. brand positoning
C. brand quality
D. brand values


7 What are vasodilators used to do?
A. decrease vascular resistance and increase blood flow
B. mimic pathogens to stimulate the immune system
C. narrow the blood vessels
D.stimulate the CNS to make the heart beat faster


8. What is the name of the condition that occurs after a specific dose of a drug is given at such regular intervals that absorption and elimination (and therefore drug plasma concentration) have become fairly constant? NAPSRx Final Exam Question and Answers
A. homeostasis
B. steady state
C. titration
D. tolerance


9. Which statement is TRUE about ocular administration?
A. Ocular administration is primarily for drugs that must cross the blood-brain barrier.
B. Ocular administration is used primarily to treat the eye.
C. Ocular administration is used when a drug must enter the bloodstream immediately.
D. Ocular administration is used when a drug must produce immediate effects on the brain or spinal cord.

10. Which entities invest’s the most money in pharmaceutical R&D?

A. Canadian pharmaceutical companies
B. the NIH
C. the U.S. Government
D. U.S. pharmaceutical companies


11. How are most drugs excreted?
A. via the bloodstream
B. via the heart
C. via the kidneys
D. via the skin


12. Over the last few decades, what has happened to legal limitations on sales’ reps discussions about off label uses?
A. Limitations have decreased.
B. Limitations have increased significantly.
C. Limitations have increased slightly.
D. Limitations have remained about the same.


13. Answer: Branding name


14. What does it mean if two drugs are at parity?
A. Both drugs are essentially in a neutral position.
B. Both drugs are generics.
C. Both drugs have exclusive preferred status.
D. The two drugs are bioequivalent.


15 Who is most likely to benefit from electronic sampling programs?
A. Everyone would benefit equally from electronic sampling programs
B. physicians in hospitals who are too busy to see representatives
C. physicians in rural areas who are not as frequently visited by representatives
D. physicians in urban areas who are too busy to see representatives


16. When referring to medication dosage, which abbreviation means “one-half’:


17 What is an internist?
A. a physician who practices internal medicine
B. a physician’s intern
C. a type of oncologist who specializes in chemotherapy
D. an internal sales representative


18. Which of the following is a type of white blood cell?
A. erythrocytes
B. insulin
C. Lymphocytes


19. Why are novice sales representatives often placed in charge of negotiating MCO formularies?
A. to become more familiar with the healthcare industry
B. to become more familiar with their territories
C. P&T committees are more receptive to new faces.
D. They are not. This job is usually reserved for more experienced reps.


20. What distinguishes pharmacodynamics from pharmacokinetics?
A. Pharmacodynamics studies a drug’s ex vivo effects.
B. Pharmacodynamics studies how drugs affect the body.
C. Pharmacodynamics studies the how the body affects drugs.
D. Pharmacodynamics studies the time required for a drug’s absorption.

21 What proportion of the drugs tested on human subjects are eventually approved by the FDA?
A. about 20%
B. about 60%
C. about 70%
D. about 95%


22. According to a study discussed in your manual, how do most physicians prefer to receive their drug samples?
A. by borrowing them from hospitals
B. by ordering them over the Internet
C. by trading them for services
D. directly from sales representatives


23. Which of the following is an example of a central value?
A. I buy Advil to show that I’m a modern consumer.
B. I like Advil because we were both born in the 80s.
C. I prefer Advil because I like the flavor.
D. I prefer Advil because it’s easier to swallow.


24. Which of the following specialties likely has the MOST emergency calls?
A. cardiology
B. psychiatry
C. urology
D. All specialists have the same number of emergency calls.


25. What affects the rate of active transport?
A. the availability of carriers. but not energy
B. the availability of energy. but not carriers
C. the availability of carriers and energy
D. neither the availability of carriers nor the availability of energy


26. Over the last few decades, what has happened to the FDA approval time for new drugs?
A. It has been lengthened to ensure safer drug products.
B. It has been lengthened to limit DTC marketing
C. It has been shortened to improve drug quality
D. It has been shortened to reduce the cost of new drug development.


27. Which of the following would NOT help improve compliance?
A. patients liking their providers
B. patients using only one pharmacist
C. pharmacists understanding how generics differ from brand name drugs
D.  support groups


28. Which entity chooses a drug’s trade name?
A. the drug’s inventor
B. the drug’s manufacturer
C. the FDA
D. the United States Pharmaceutical Council


29. What type of stem cells are obtained from embryos and can develop into any cell type?
A. multipotent
B.  pluripotent
C. totipotent
D. All stem cells can develop into any cell type.


30. As the price a patient pays for a prescription increases, what happens to the likelihood that the patient will fill it?
A. It decreases.
B. It increases.
C. It remains unaffected because the prescription is needed.
D. It remains unaffected because the prescription’s increased cost is offset by its perceived value.


31. Most involuntary movements come from which type of muscle tissue?
A. cardiac and smooth
B. only skeletal
C. skeletal and cardiac
D. skeletal and smooth


32. Which of the following is NOT one of the body’s major organ systems?
A. the cardiovascular system
B. the cellular system
C. the gastrointestinal system
D.  the musculoskeletal system


33. How do most drugs exert their primary physiological effects?
A.  by activating synapses between different types of tissues
B. by binding to cell receptors that are sensitive to their presence
C. by inhibiting synapses between different types of tissues
D.  through genetic mutation


34. What is the most reliable source of information for determining therapeutically equivalent drug products?
A. AMA guide
B. Blue Book
C. FDA drug list
D.  Orange Book


35. What does subcutaneous mean?
A. beneath the intervention
B. beneath the muscle tissue
C. beneath the outer skin
D. beneath the suture


36. What should a sales representative do if all of the prime spaces in a drug cabinet are coccupied?
A. ask staff for permission to move some of the other products in the cabinet
B. ask staff for permission to throw away expired products in the cabinet
C. ask the doctor if he still needs some of the other products in the cabinet
D. surreptitiously move your largest competitors’ products out of the way


37. It is inappropriate for physicians’ prescribing behaviors to be educated by their personal tastes and idiosyncrasies


38.The FDA defines API as the active__ ingredient in a drug, which produces the desired change in the body.
A. pharmaceutical
B. positive
C. potent
D.  primary


39. What are the 2 legal classifications of wholesalers?
A. distributors and supply chains
B. pharmacists and NAMs
C. primary and secondary wholesale distributors
D. retailers and institutions


40.What term describes the usage of a medication for purposes other than the FDA-approved indications on the labeling?
A. contraindicative indication
B. off-indication usage
C or D. off-label


41. What is the acronym for pharmacokinetics?
D. pT


42. The dosage range of a drug that is both safe and beneficial is known as the therapeutic window.


43. What is typically NOT a characteristic of a pharmaceutical sales rep?
A. Pharmaceutical sales reps are authentic and real.
B. Pharmaceutical sales reps are creative.
C. Pharmaceutical sales reps are focused.
D. Pharmaceutical sales reps are not concerned about competitors.


44. What entity grants drug patents?
A. the FDA
B. the FDA if the drug is over-the-counter and the U.S. Patent and Trademark Office if the drug is prescription
C. the FDA if the drug is prescription and the U.S. Patent and Trademark Office if the drug is over-the-counter
D. the U.S. Patent and Trademark Office


45. Which of the following refers to all active and inert pharmaceutical ingredients in a drug, including fillers and colors?
A. formulation
B. mycoplasma
C. peptide
D. saccharide


46. What is the difference between potency and efficacy?
A. Doctors prefer more potent drugs.
B. Drug manufacturers prefer more potent drugs.
C. Potency refers to the drug’s effectiveness. while efficacy refers to its strength.
D. Potency refers to the drug’s strength, while efficacy refers to its effectiveness.


47. What is the minimum level of education required for a nurse practitioner?
A. a certification program
B. an associate’s degree
C. a bachelor’s degree
D. a graduate degree


48. How many names must a drug have?
A. at most three
B. at least three
C. at most five
D. at least five


49. How has a longer development time increased the cost of bringing a new drug to market?
Answer: Increasing the cost of capital


50. Senior citizens consume over times as many pharmaceuticals as people under 65.
A. three
B. five
C. ten
D. fifteen


51. What agency regulates the distribution and use of narcotics?


52. What is passive diffusion?
A. a type of pinocytosis
B. membrane transport via vesicles
C. the use of energy to help a substance pass from a low concentration gradient to a high one
D. when a substance freely moves through a membrane from a high concentration gradient to a low one


53. What are the MAIN categories of drugs under FDA jurisdiction?
A. active drugs and active placebos
B. biopharmaceuticals and nutraceuticals
C. non-prescription and nutraceuticals
D. prescription and non prescription


54. Answer: Oxytocin


55. What are all metabolites?
A. active substances
B. inactive substances
C. injections
D. products of metabolism

56. When a drug is administered orally, where does first-pass metabolism occur?
A. intestine
B. liver
C. pancreas
D. stomach


57. What is the medical term for swelling?
A. assay
B. edema
C. instillation
D. protease


58. Which of the following is NOT part of the Seven Step Cascade of Emotion?
A. be a consultant. not a rep
B. identify what your product does
C. reflect
D. visualize the power of 10


59. Which part of a clinical research paper is frequently referred to as the road map?
A. abstract
B. findings
C. letter to the editor
D . methods


60. Which of the following is a main active ingredient in lung surfactants?
A. animal lung extract
B.  germicides
C.  sympathomimetic drugs
D.  theophylline


61. What does parenteral mean?
A. child prescriptions
B. injection
C. oral
D. tablet


62. Which term denotes a type of substance that enhances the action of a drug or antigen?
A. adjuvant
B. indicated
C. ligase
D peptide


63. If a sales representative’s product is placed on the second tier of a standard three-tier formulary, which of the following is most likely true?
A. It has not been reviewed by the P&T committee.
B. It is in a neutral position unless it is at parity with other drugs.
C. It probably has exclusive preferred status if it is not at parity with any other drugs.
D. It will essentially sell itself if it is granted exclusive preferred status.

64. Which of the following is NOT one of the four basic transport mechanisms?
A. active transport
B. homeostasis
C. passive diffusion
D. pinocytosis


65. Which statement accurately describes a relationship between drug agonists and antagonists?
A. Agonists and antagonists can be used together.
B. Agonists and antagonists should not be used together.
C. Antagonist drugs activate receptors. while agonists block access to receptors.
D. Antagonists are endogenous whereas agonists are man-made.

66. What is the study of the effects and movement of drugs in the human body?

A. anatomy
B. antology
C. clinical pharmacology
D. pathology


67. According to your manual, what is a common complaint that physicians have about traditional sampling methods?
A. that drug sample supply is too unpredictable
B. that patients are less likely to take free samples because they think they are lower quality
C. that patients do not like seeing drug representatives in their offices
D. that they receive too many drug samples


68. Which of these entities is formed by two or more hospitals or other healthcare entities to negotiate reduced rates with its aggregated purchasing power?
B. In-state wholesaler


69. What is another name for a drug derived from a biologic compound?
A. large molecule
B. oligonucleotide
C. orgaanism
D. small molecule


70. What is the most common policy regarding pharmaceutical reps dispensing drug samples in hospitals?
A. By federal law. drug sampling is permitted in all hospitals.
B. By federal law. it is up to individual physicians. not the hospital.
C. Drug sampling is encouraged. but not required.
D. Drug sampling is often forbidden.


71 Which of the following would help you build trust with a physician?
A. asking if he or she is having any problems with the managed care coverage of your products
B. repeating a question you already asked
C. surprising the office staff with a new poster in the break room
D. None of these would help you build trust with a physician.


72. What term denotes the difference between the usual effective dose and the dose that induces severe or life-threatening side effects?
A. dose-response relationship
B. margin of safety
C. the placebo effect
D. therapeutic window


73. What are excipients?
A. a type of cell receptor to which antagonists bind to decrease the effects of the body’s natural agonists
B. another term for generic equivalents
C. sites of action besides the target sites of action
D. the inert ingredients in a drug formulation


74. What is another term for the AWP?
A. dock-to-dock price
B. float price
C. list price
D. non-stock price

75. Which of these is the most likely use for a uterotonic agent?

A. to induce labor
B. to make the urine more alkaline
C. to supplement oral food intake
D. to treat hyperthyroidism


76. As of November 2013, which of these countries has legalized DTC advertising of prescription drugs?
A. Canada
B. Japan
C. Spain
D. none of these


77. Why are oral drugs often taken on an empty stomach?
A.  to be more wholly absorbed by the stomach
B. to minimize absorption by the intestine
C.  to minimize nausea

D. to pass through the stomach more quickly

78. What is one factor that differentiates community health centers from hospitals?
A.  Community health center formularies are more restrictive.
B. Community health centers have higher reimbursement rates.
C. Newer brand name drugs are easier to access at community health centers.
D. None of these


79. How does drug sampling provide a social benefit?
A. Doctors donate their unused drug samples to charities.
B. Doctors often use drug samples to treat patients who otherwise could not afford it.
C. It allows patients to try out different prescription medications before consulting with physicians.
D.  Drug sampling provides a social benefit in all of these ways.


80. Which medical term denotes the use of a stethoscope to listen to the heart?
A. auscultation
B. cardioversion
C. catheterization
D. echocardiography


81. What do enteric coatings do?
A. facilitate vomiting
B. help drugs dissolve in the stomach
C. help drugs enter the bloodstream more quickly
D. prevent dissolution in the stomach


82. What is the duration of exclusivity for orphan drugs?
A.  6 months
B. 1 year
C.  7 years
D.  15 years


83. What do National Account Managers do?
A. act as the sales reps’ primary point of contact with the rest of the corporation
B. manage the FDA approval process
C. negotiate contracts with MCOs and PBMs
D.  sell only to pharmacies

84. What does it usually mean if a drug recall is voluntary?
A. Pharmacies may choose whether to return the drug or dispense it.
B. The FDA has determined that the drug is perfectly safe. but ineffective.
C. The manufacturer has recalled the product on its own. but negotiated with the FDA beforehand.
D. The manufacturer has recalled the product without negotiating with the FDA.

85. Which phase of clinical trials is also known as the pivotal phase?
A. Phase I
B. Phase III
C Phase IV
D. Phase IX


86. During which phase of clinical trials is the new drug’s safety and effectiveness first tested in the target group? NAPSRx Final Exam Question and Answers
A. preclinical
B. Phase I
C. Phase II
D. Phase III


87. How do antacids work?
A. by increasing blood flow to the stomach
B. by lowering gastric pH
C. by raising gastric pH
D. by suppressing cholesterol formation by the liver


88. What is one of the biggest time wasters for a pharmaceutical sales rep?
A. Caterers
B. Pharcists
C. receptionists
D. travel time


89. What happens when equilibrium is reached?
A.  equal numbers of molecules cross the membrane in both directions
B.  molecules stop moving
C. the concentration gradient decreases indefinitely
D. the concentration gradient increases indefinitely


90. What are the most common vectors used in gene therapy?
A.  autologous antigens
B. liposomes
C. naked DNA
D. viruses


91. What is the percentage fee that the dispenser pays the wholesaler for distribution?
A. margin fee
B. recharge
C. standard fee
D. upcharge


92. What is the difference between a chronic (or continuing) reaction, and a delayed reaction?
A. Chronic reactions are exaggerated. whereas delayed reactions are idiosyncratic.
B. Chronic reactions occur only during treatment. whereas delayed reactions only occur during withdrawal. NAPSRx Final Exam Question and Answers
C. Chronic reactions persist for a long time. whereas delayed reactions take some time to develop.
D. Delayed reactions are always idiosyncratic. but chronic reactions are not.


93 What is clinical effect?
A. federally funded research condition
B. the effect of maximum dosage
C. the response produced by a medication
D. the use of treatment drugs in chemotherapy


94. Which of the following is an example of noncompliance?
A. a patient forgetting to take a drug at a specified time of day
B. a patient taking a drug. but only because it has been court-mandated
C. a pharmacist dispensing a generic equivalent of a drug instead of the brand name
D. a physician refusing to prescribe a drug because he or she does not trust the clinical studies on it


95. What is the average circulation time of blood?
A. about a minute
B. about 5 minutes
C. about 5 to 10 minutes depending on the patient’s age and health conditions
D. about 10 minutes


96. What is one way in which pharmaceutical selling is different from selling in most other industries?
A. In pharmaceutical sales. the decisions-makers. consumers. and payers are usually the same entity.
B. Pharmaceutical selling takes less time because doctors are so busy.
C. Representatives do NOT sell to the end user of the product.
D. Representatives DO sell to the end user of the product.


97. From what types of entities do primary wholesale distributors buy most of their drugs?
A. brokerages
B. buying clubs
C. manufacturers
D. physicians

98.What is the Office of the Inspector General (01G)?
A. a department in pharmaceutical companies
B. an arm of the Department of Health and Human Services
C. an arm of the European Medicines Agency D an arm of the FDA


99. What are doctors required to consider when deciding whether or not to prescribe a particular drug?
A. quantity of life over quality of life
B. that no drugs with adverse effects should ever be used
C. the inferiority of OTC drugs
D. the severity of the disorder being treated and the effect it has on the patient’s quality of life

100. Which entity assigns a new drug its generic names?
A. the drug’s inventor
B. the Food and Drug Administration
C. the United States Adopted Name Council
D. the United States Pharmaceutical Council


101. Drugs can be used days beyond their expiration date.
A.  2-7 days. depending on the most current monograph.
B.  2-90 days. depending on state laws
C. 7-90 days. depending on the type of drug and its therapeutic class.
D. none of these


102. What is necessary for a drug to be excreted extensively via the kidneys?
A. The drug must be water-soluble. and not bind too tightly to proteins in the bloodstream.
B. The drug must have a phospholipid bilayer and be non-water-soluble.
C. The drug must have a phospholipid bilayer and bind well to proteins in the bloodstream.
D. The drug must not be water-soluble. NAPSRx Final Exam Question and Answers


103. Which organization or individual initiates the clinical trial and finances the study?
A. clinical research organization
B. investigator
C. researcher
D. sponsor


104. The name describes the atomic or molecular structure of a drug.
A. chemical
B.  generic
C. pharmaceutical
D. proprietary


105. Under PhRMA Code, is it acceptable or unacceptable for a pharmaceutical sales rep to take a physician and the physician’s spouse to a fundraising dinner?
A. acceptable if only the physician attends
B. acceptable if only the physician attends. and the total is under $100
C. acceptable if the total is under $100
D. unacceptable


106. The Hatch-Waxman Act is considered the most significant drug-related affecting the pharmaceutical industry since 1962.
A. experiment
B. legislation
C. process
D. research


107. What term denotes the the extent, quality, or degree to which a substance is poisonous or harmful to the body?
A. caliber
B. chronicity
C. indication
D. toxicity


108. What issue has MOST encouraged consumers’ desire to see more OTC medications?
A. a weaker patients’ rights movement
B. lack of insurance coverage
C. less reliance on the Internet
D. proliferation of herbal remedies


109. What is the degree to which a medication produces a therapeutic effect?
A. diffusion
B. efficacy
C. protease
D. vector


110. What is the most important benefit of electronic prescribing?
A. Choice
B. cost
C. inquiries
D.  safety


111. When does the FDA regulate generic drugs?
A. only if they are branded generics
B. only if they have been contested
C.  always
D never


112. Which phase of trials largely determines the clinical dose?
A. preclinical trials
B. Phase II trials
C. Phase III trials
D. Phase IV trials


113. What is an advantage of inactivated vaccines over attenuated vaccines?
A.  Inactivated vaccines are less expensive to prepare.
B. Inactivated vaccines have a higher probability of eliciting the desired immunological response.
C. Inactivated vaccines have a more stable shelf life.
D.  Inactivated vaccines only require a single dose.

114. Which medical term denotes a low supply of oxygen due to low blood flow?
A. potentiation
B. ischemia
D. titration


115. What are the two main types of prescription drug marketing?
A. (1) marketing to insurance companies. and (2) marketing to pharmacies
B. (1) PBM marketing. and (2) marketing to governments
C. (1) professional physician promotions. and (2) direct-to-consumer advertising
D. (1) publicly-funded marketing. and (2) physician-funded marketing. NAPSRx Final Exam Question and Answers.


116. What is the site of delivery for subcutaneous injections?
A. fatty tissue beneath the surface of the skin
B.  lymphatic tissue
C. muscle tissue
D. the stomach, via a special type of needle


117. What must be contained in the Description section of a pharmaceutical package insert?
A. adverse effects
B. mechanism of action
C. pharmacokinetics
D. the proprietary name and the established name


118. What is the study of a medication’s effects as it travels through the body?
A. pharmacodynamics
B. pharmacogenetics
C. pharmacogenomics
D. pharmacokinetics


119. Customers purchase products from people they like, trust, and respect. This is called the  
A. closing of the sale
B. first time advantage
C. likeability factor
D. power of knowledge


120. What is penicillin’s primary mechanism of action?
A. It disturbs bacterial cell wall synthesis.
B It inhibits the production of viruses.
C. It prevents proper DNA replication.
D. It sends a messenger to the bone marrow to produce extra white blood cells


121. According to your manual, how has the U.S. healthcare marketplace changed in the last few decades?
A. Fewer and fewer prescription drugs have been made available as OTCs.
B. Managed care has been increasingly replaced by more patient-centered approaches.
C. The aging Baby Boomer generation has begun demanding more personalized attention.
D. There has been decreased emphasis on preventive health.


122. How does pharmaceutical marketing help narrow the treatment gap?
A. It encourages patients to take more active roles in their healthcare.
B. It makes doctors more skeptical of the pharmaceutical ind

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